Dr Mark Horowitz MBBS PhD is is the founder of the Psychiatric Drug Deprescribing Clinic at North East London NHS Foundation Trust, Clinical Research Fellow in Psychiatry at North East London NHS Foundation Trust (NELFT), Visiting Lecturer at King’s College London, an Honorary Clinical Research Fellow at University College London, and co-founder of Outro Health, a medical deprescribing service. He has a PhD from the Institute of Psychiatry, Psychology and Neuroscience at King’s College London in the neurobiology of depression and antidepressant action.

His own difficulty of coming off psychiatric medications has informed much of his work. He has an interest in rational psychopharmacology and deprescribing psychiatric medication. He is the lead author of the 2024 Maudsley Deprescribing Guidelines and is an associate editor of the journal Therapeutic Advances in Psychopharmacology.

He has written several papers about safe approaches to tapering psychiatric medications including publications in The Lancet Psychiatry, JAMA Psychiatry and Schizophrenia Bulletin. He co-authored the recent Royal College of Psychiatry guidance on ‘Stopping Antidepressants’, and his work informed the recent NICE guidelines on safe tapering of psychiatric medications, including antidepressants, benzodiazepines and z-drugs. He has been commissioned by Health Education England to prepare a teaching module on how to safely stop antidepressants.